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CASE REPORT
Year : 2021  |  Volume : 1  |  Issue : 4  |  Page : 155-158

Pseudomembranous colitis due to Cytomegalovirus infection during SARS COVID-19 convalescence


1 Department of Medical Gastroenterology and Hepatology, SRM Institute for Medical Science Hospital, Chennai, Tamil Nadu, India
2 Department of Pathology, SRM Institute for Medical Science Hospital, Chennai, Tamil Nadu, India

Correspondence Address:
Rohan Yewale
Department of Medical Gastroenterology and Hepatology, SRM Institute for Medical Science Hospital, No. 1, Jawaharlal Nehru Salai, 100 Feet Road, Vadapalani, Chennai - 600 026, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ghep.ghep_24_21

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Pseudomembranous colitis (PMC) is a well-known entity with an increasing prevalence in the current post antibiotic era. Its endoscopic and histological morphology is often considered synonymous with Clostridioides difficile-associated colitis. Cytomegalovirus (CMV) infection is a less commonly reported cause of PMC. We report an interesting case of a 61-year-old gentleman with an acute-onset, inflammatory diarrhea during SARS COVID-19 convalescence who was found to have features consistent with PMC on colonoscopy. However, histological and immunohistochemistry analysis of colonic biopsies revealed the presence of CMV infection in the absence of C. difficile toxins on stool assay.


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